Updated: March, 2001
CURRICULUM VITAE
| PERSONAL | |
| Name: | Kathleen Helen Berecek, Ph.D.
|
| Place of Birth: | Chicago, Illinois
|
| Citizenship: | U.S.A.
|
| Current Professional Status: | Professor of Physiology and Biophysics
Associate Scientist, Vascular Biology and Hypertension Program Senior Scientist, Cell
Adhesion and Matrix Research Center
|
|
| Mailing Address: | University of Alabama at Birmingham
Department of Physiology and Biophysics 1530 3rd Avenue South, MCLM 988
Birmingham, AL 35294-0005
|
|
| Office Phone Numbers: | (205) 934-2411 or (205) 934-6239
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|
| Office Fax Number: | (205) 934-5787
|
|
| Email Address: | Berecek@uab.edu | |
|
|
| EDUCATION | |
| 9/64 - 9/68 | B.S., St. Xavier College, Chicago, Illinois |
| 9/69 - 5/71 | M.S., University of Michigan, School of Nursing, Ann Arbor, Michigan |
| 9/71 - 10/76 | Ph.D., University of Michigan, Dept. of Physiology, Ann
Arbor, Michigan Thesis Advisor: Dr. David F. Bohr
|
| PREVIOUS WORK EXPERIENCE | |
| 10/74 - 7/76 | Assistant Professor, University of Michigan, School of Nursing Graduate Program, Ann Arbor, Michigan |
| 2/75 - 8/75 | Consultant, Program for Urban Health Research, University of Michigan, Ann Arbor, Michigan |
| 10/76 - 12/77 | Postdoctoral Scholar, Department of Physiology (Dr. David F. Bohr) University of Michigan, Ann Arbor, Michigan |
| 1/78 - 9/79 | Research Associate, Department of Pharmacology (Dr. Franz Gross), University of Heidelberg, Heidelberg, Fed. Rep. Germany. Supported by Deutscheforschungsgemeinschaft Sonderforschungsbereich Cardiovaskulares 90 |
| 10/79 - 6/81 | Postdoctoral Scholar, Department of Pharmacology and the Cardiovascular Center, University of Iowa (Dr. Michael J. Brody), Iowa City, Iowa |
| 7/81 - 10/85 | Assistant Professor Physiology and Biophysics and Associate Scientist, Cardiovascular Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama |
| 10/85 - 10/91 | Associate Professor of Physiology and Biophysics; Associate Scientist, Cardiovascular Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama |
| 10/91 - Present | Professor of Physiology and Biophysics; Associate Scientist, Vascular Biology and Hypertension Program; Senior Scientist, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama |
| 1/93 – 1/99 | Appointed as Associate Editor American Journal of Physiology: Heart and Circulatory Physiology |
| 4/93 - 6/96 | Appointed as Chairman of the Publications
Committee, AHA Council for High Blood Pressure Research and Guest Editor of the Supplement
to Hypertension
|
| AWARDS AND HONORS | |
| 9/67 - 9/68 | Mercy Scholarship |
| 10/79 - 6/81 | University of Iowa, Cardiovascular Center Fellowship |
| 11/81 | Finalist - L. N. Katz Research Prize, American Heart Association |
| 12/82 | Elected Fellow of the Council on Circulation of the American Heart Association |
| 9/83 | Elected Fellow of the Council for High Blood Pressure Research, American Heart Association |
| 4/84 | Elected Fellow of the Cardiovascular Section, American Physiology Society |
| 6/88 | Awarded Young Scholars Award, the American
Society of Hypertension ($10,000)
|
| GRANTS | |
| 9/69 - 5/71 | NIH Professional Nurse Traineeship, PHS - 02229 |
| 9/71 - 12/76 | NIH Special Predoctoral Fellowship, 5-FO4, NU 27402-03 |
| 10/76 - 10/77 | NIH-NHLBI Postdoctoral Fellowship HL-5384 F 32 |
| 4/82 - 3/85 | USPHS Grant: National Heart, Lung, Blood Institute, 1R01 HL 28545-01 CVB, 04/01/82-03/31/85 ($124,315) |
| 7/82 | Established Investigator Award, American Heart Association 7/1/82-6/30/87 $150,000) |
| 12/83 - 11/86 | USPHS Grant: NHLBI 1 R01 HL 31515 12/01/83-11/30/86 ($180,155) |
| 4/85 - 3/90 | Competitive Renewal USPHS Grant: NHLBI HL 28545, 04/01/85-03/31/90 $296,902) |
| 12/86 - 11/89 | Competitive renewal, USPHS Grant NIH NHLBI 31515, 12/01/86-11/30/89 ($361,760) |
| 6/88 | Awarded Young Scholars Award, the American Society of Hypertension ($10,000) |
| 7/90 | Competitive renewal, USPHS Grant NIH NHLBI 31515, 07/01/90-06/30/95 ($701,195) |
| 6/92 | USPHS Grant: NHLBI R01 HL45665, 7/1/92-6/30/96 ($898,303) |
| 9/95 | Competitive renewal NHLBI - HL31515, 9/1/95-8/31/99 ($778,967) |
| 5/97-8/99 | Supplement Award to K.H. Berecek and A.K. Keaton for HL31515 ($21,581) |
| 7/99 - 6/04 | NIH-NHLBI -A predoctoral training program in cardiovascular pathology. Co-PI (Total Direct Costs $958,235) |
| 4/1/00-3/31/05 | Competitive renewal NHLBI-HL31515-16, Brain and cardiac angiotensin II in hypertension, 50% effort, 4/1/00-3/31/05 (775,000) |
MEMBERSHIP IN PROFESSIONAL ORGANIZATIONS
American Physiological Society (regular member); Primary member of APS-Cardiovascular
Section; Secondary member of Neural
Control Section; Tertiary Member of Salt and
Water Homeostasis FASEB American Heart Association, Councils on High Blood
Pressure Research, Basic Sciences, and
Circulation and Atherosclerosis, Thrombosis and Vascular Disease
Sigma Xi
Society for Experimental Biology and Medicine (elected member)
American Federation for Clinical Research (elected member)
Society for Neurosciences (elected member)
Inter-American Society for Hypertension Research (elected member)
American Society for Hypertension
EDITORIAL BOARDS
Hypertension, January 1982 - 1985
American Journal of Physiology: Heart and Circulatory Physiology, 1982 - 1986
Circulation Research, 1989 - 1992
Hypertension, 1989 - present
AHA Council on High Blood Pressure Research Committee: Guest Editor for Journal Issue of Proceedings for yearly meetings, 1993 - 1996
Associate Editor, Am. J Physiology: Heart and Circulatory Physiology, 1993 -1996
Hypertension Research, 1993 - 1999
Clinical and Experimental Pharmacology and Physiology, 1998 – 2001
| STUDY SECTION/GRANT REVIEW SERVICES |
|
| 1984 | Member of Review Committee. NHLBI - "Pathogenesis of Essential Hypertension" RFA - NIH - NHLBI - DHVD - 84G-I |
| 1985 | Ad Hoc member Cardiovascular and Renal Study Section, NIH-NHLBI (CVB) |
| 1986 | Ad Hoc member Experimental Cardiovascular Study Section, NIH-NHLBI |
| 1986 | Member special NIH-NHLBI Cardiovascular and Pulmonary Study Section. Research grant evaluation. Telephone Conference |
| 1987 | Member Special Review Section DRG, SSS-X Research Grant Evaluation.Telephone Conference |
| 1987-1991 | Member of NIH-NHLBI Experimental Cardiovascular Sciences Study Section |
| 1988 | Ad Hoc member, Supplement Application "Neurohumoral and Receptor Mechanisms in Hypertension" PI: Dr. Morton Printz |
| 1991-present | Member of Physiology Study Section for Oklahoma Center for the Advancement of Science and Technology |
| 1991-1994 | Reviewer, American Institute of Biological Sciences, (NASA), Space Counter Measures Proposals |
| 1991-1994 | AHA, Cardiovascular Regulation Study Section |
| 1/93 | DDK-AHR-06/NIDDK/RB - Site visit committee for Dr. Robert Shrier's program project, Denver, CO |
| 1994-present | Reviewer for the John Sealy Memorial Endowment Fund, University of Texas, Galveston, Texas |
| 1995-2000 | Chair, American Heart Association, Cardiovascular Regulation I Study Committee |
| 1997 | Member, NIH: Program Project Review Committee for HL14388, Francois M. Abboud: Integrative Neurobiology for Cardiovascular Regulation |
| 1999 | DDK-AHR/NIDDK/RB Site Visit for Dr. Robert Shrier’s Program Project, Denver, CO |
| 2000 | State of Louisiana Tobacco Money Research Initiative (grant reviewer) |
COMMITTEE APPOINTMENTS-PROFESSIONAL ORGANIZATIONS
| American Heart Association | |
| 1985-1988 | Member, Executive Committee, AHA Council on Circulation |
| 1986-1989 | Member, Program Committee, AHA Council for High Blood Pressure Research (HBPR) |
| 1990 | Member of AHA Task Force for Hypertension Research |
| 1991-1993 | Member, Publications Committee, AHA Council for HBPR |
| 1993-1996 | Member, Program Committee, AHA Council for HBPR |
| 1993-1996 | Chair, Publications Committee, AHA Council for HBPR |
| 1993-1996 | Guest Editor, Proceedings of the Scientific Meeting of Council for HBPR |
| 1993-2000 | Member, Executive Committee Council for HBPR |
| 1995-1997 | Member, Long Range Planning Committee |
| 1997 | Organized and Co-Chaired Second Hypertension Summer School for Council for HBPR, Castine, Maine |
| 1995-2000 | Member of AHA National Research Committee, Representative of the Council for HBPR |
| 1997-2000 | Member, Program Committee International Society of Hypertension Meeting, ISH 2000 |
| 1999 | Organized and Co-Chaired Third Hypertension Summer School for Council for HBPR, Boulder, Colorado |
| 1995-2000 | Chair, AHA National Study Section – Cardiovascular Regulation I |
| American Physiological Society |
|
| 1986-1989 | Member, Committee on Committees |
| 1993-1996 | Appointed as Associated Editor, American Journal of Physiology: Heart and Circulatory Physiology |
| 1996 | Elected Secretary of the Cardiovascular Section of the APS |
| 1997 | Treasurer, Cardiovascular Section of the APS |
| 1998-2001 | Chair, Cardiovascular Section, APS |
| 1998-2001 | Member, APS Section Advisory Committee |
| 1999 | Member, APS Strategic Planning Committee |
| 1999 | Member, Nominating Committee |
| 1999-present | Member, Program Committee, APS Cardiovascular Section |
| 1999-present | Member, Steering Committee, APS Cardiovascular Section |
| 1999-present | Joint APS Council and SAC Committee
|
| American Society of Hypertension | |
| 1995-present | Member, Membership Committee
|
| International Society for Hypertension | |
| 2000 | Member, Program Committee, ISH Year 2000
Meeting
|
| CONSULTING POSITIONS | |
| 1975 | University of Michigan, Program for Urban Health Research Hypertension Project, Ann Arbor, Michigan |
| 1988 | External advisor, Program Project in Hypertension Research, Case Western Reserve University, Cleveland, Ohio, PI: Dr. Janice Douglas |
| 1990 | Discussant, American Heart Association Prevention Conference II-Hypertension |
| 1990 | AHA Task Force for Hypertension Research |
| 1992 | Neurohypophysis' Meetings Planning Committee |
| 1993-present | Consulting Editor of Hypertension |
| 1994 | Consultant for Bristol-Myers, Squibb |
| 2000 | Mentor, APS-NIDDK Minority Program for Keith
Jackson and Jurandir Dalle Lucca
|
| ADMINISTRATIVE APPOINTMENTS/ACTIVITIES AT UAB | |
| 1982-present | Faculty member Hypertension Training Program |
| 1984 | Member of Organizing Committee for Southeastern Regional Neuroscience Meeting, Birmingham, May, 1984 |
| 1983-1986 | Organization and administration of a work-in-progress research seminar for postdoctoral students participating in the Hypertension Training Grant of the Cardiovascular Research and Training Center |
| 1984-1986 | UAB Animal Use Committee |
| 1984-1990 | Administration of the Hypertension Seminar Program for the Cardiovascular Research and Training Center |
| 1986-present | Faculty Member, UAB Neuroscience Graduate Training Program |
| 1986-present | Faculty Member, UAB M.D./Ph.D. Training Program |
| 1988-1998 | Graduate Committee, Department of Physiology and Biophysics |
| 1988-present | Advisory Committee of the Hypertension Training Program |
| 1988-present | Executive Committee Hypertension Program |
| 1991-1998 | Department of Physiology and Biophysics Graduate Student Committee |
| 1991-2000 | Member of the Dept. of Physiology/Biophysics Promotions and Tenure Committee |
| 1992 | Judge for Graduate School Research Day |
| 1993 | Judge for Sigma Xi Graduate Student Research Day |
| 1994 | Judge International Science Fair |
| 1996 | Appointed Senior Scientist, Cell Adhesion and Matrix Research Center. |
| 1997 | Joint Health Sciences Faculty Status Committee |
| 1997 | BSAC Subcommittee on Graduate Education |
| 5/00 | Steering Committee, Predoctoral Training Program in Cardiovascular Pathology |
| 5/00 | Joint Health Sciences Faculty Status Committee |
| 1/01 | Chair, Department of Physiology &
Biophysics Promotions and Tenure Committee
|
| SERVICE TO ALABAMA (OUTSIDE UAB) | |
| Presentations to medical societies, civic organizations, etc. and membership in community organizations: | |
| 1983 | Gave talk on cardiovascular research for the Marengo County Chapter of the Alabama Heart Association |
| 1983 | Gave lecture on hypertension research for physicians and allied health personnel in Demopolis |
| 1984 | Poster (research) presentation for the Alabama Heart Association Awards Dinner, Birmingham |
| 1985 | Poster (research) presentation for the Alabama Heart Association Meeting |
| 1986 | Research talk, American Heart Association, Alabama Affiliate, Volunteer/Staff Leadership Conference, Shelby County, Alabama |
| 1988 | Science Fair Judge - Research Learning Center School, Birmingham, AL |
| 1988 | "Out of School Credit Program" Intern Segment, Jefferson County Board of Education, Birmingham, Alabama (Sandra Lo) |
| 1989-1998 | Preceptor Summer Student Research Program (Paras Shah, Sandra Lo, LaToya Gains) |
| 1990-1998 | Mentor "Out of School Credit Program" Intern Segment, Jefferson County Board of Education (Paras Shah, Chad Johnson, Chris Gebhardt, AND Sandra Lo) |
| 1997 | Seminar, Department of Physiology, UAB
|
| TRAINEES | |
| Graduate Students | |
| Primary Advisor – Thesis Committee Chair | |
| 1986-1990 | Bruce Swords (defended 11/90) |
| 1988-1991 | Mary Thorstad |
| 1988-1992 | Jian-Nan Wu, M.D. (defended 6/92) |
| 1991-1995 | Doug Moellering (ended with M.S. degree) |
| 1992-1996 | Christopher Regan (defended 8/96)
|
| Secondary Advisor – Thesis Committee | |
| 1982 | Gorden L. Pullen, The Chicago Medical School, Chicago, IL |
| 1990-1992 | Naimin Wei |
| 1990-1992 | Nicholas Gantenberg |
| 1992-1994 | Marybeth Vono |
| 1992-1998 | Rachael Hunt |
| 1993-995 | Pei Yan Chen |
| 1994-1996 | Nicole Mashburn |
| 1993-1996 | Karen Beth Beason |
| 1996-1999 | Nipon Chattapakorn |
| 1996-1999 | Brad White |
| 1995- | Jonathan Shelton |
| 1999- | Chastity McRae
|
| Undergraduate Students | |
| 1988-1990 | Sandra Lo, High School Honors Student |
| 1989-1991 | Preceptor, Summer Student Research Program (Paras Shah, Sandra Lo, and LaToya Gaines) |
| 1990-1992 | Mentor, "Out of School Credit Program", Intern Segment, Jefferson Board of Education (Paras Shah, Chad Johnson, Chris Gebhart and Sandra Lo) |
| 1991-1992 | David Edwards, Honors Biology Student |
| 1998 | T’wanda Moore, Minority Training Program High School Students |
| 1998 | John Paul Bevel, Minority Training Program
|
| Minority Hypertension Training Program | |
| 1984 | Karen Banks |
| 1985 | Addie Jo Berry |
| 1986 | David Denrue
|
| Postdoctoral Trainees | |
| 1984-1986 | David Shier, Ph.D. |
| 1986-1988 | Karen M. Wilson, Ph.D. |
| 1986-1988 | Savio Cheng, Ph.D. |
| 1995-1998 | Alphonso K. Keaton, Ph.D. |
| 2000- | Juan Bernal, M.D.
|
| INVITED SEMINARS | ||
| 5/77 | Instituto de Ricerche Farmacologiche Mario Negri, Milan, Italy | |
| 12/77 | Imperial Chemical Industries, Chesire, England | |
| 6/78 | University of Antwerp, Department of Pharmacology, Antwerp, Belgium | |
| 11/78 | Institut de Recherche Cardio-Angieologique, Fribourg, Switzerland | |
| 4/79 | Centre de Recherche, Merrell International, Strasbourg, France | |
| 6/79 | University of Antwerp, Department of Pharmacology, Antwerp, Belgium | |
| 7/79 | University of Lund, Department of Physiology, Lund, Sweden | |
| 9/79 | Imperial Chemical Industries, Chesire, England | |
| 6/80 | Henry Ford Hospital, Hypertension Unit, Detroit, Michigan | |
| 5/81 | University of Tennessee, Department of Physiology, Memphis, Tennessee | |
| 9/81 | Chicago Medical College, Department of Physiology, Chicago, Illinois | |
| 9/81 | Johns Hopkins, Department of Physiology, Baltimore, Maryland | |
| 2/82 | Pennsylvania State University, Department of Biology, University Park, Pennsylvania | |
| 9/82 | Imperial Chemical Industries, Chesire, England | |
| 9/82 | University of Heidelberg, Department of Pharmacology | |
| 9/82 | Hypertension Research Unit, Henry Ford Hospital, Detroit, Michigan | |
| 10/82 | CIBA-Geigy Ltd, Basel, Switzerland | |
| 4/83 | Michigan State University, Department of Physiology | |
| 6/83 | Cantonsspital, Basel, Switzerland | |
| 7/83 | Hospital Nestle, Lausanne, Switzerland | |
| 2/84 | Department of Physiology, Emory University, Atlanta, Georgia | |
| 3/84 | Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland | |
| 10/84 | Smith, Kline and French Laboratories, Philadelphia, PA | |
| 5/85 | Wayne State University, Department of Physiology | |
| 5/85 | Hypertension Research Unit, Henry Ford Hospital | |
| 5/85 | University of Michigan, Department of Physiology | |
| 6/85 | CIBA-Geigy Ltd., Basel, Switzerland | |
| 2/86 | Medical College of Wisconsin, Department of Physiology | |
| 3/86 | Heart Institute Hospital das Clinicas Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil | |
| 3/86 | Department of Physiology &Pharmacology, Universidade Federal de Pernambuco Recife, Brazil | |
| 9/86 | Research Talk, American Heart Association, Alabama Affiliate, Volunteer/Staff Leadership Conference, Shelby County Alabama | |
| 5/87 | InterAmerican Society for High Blood Pressure Research, Buenos Aires, Argentina | |
| 7/87 | University of Heidelberg, Department of Pharmacology, Heidelberg, West Germany | |
| 7/87 | FASEB summer workshop "Neural Control of the Circulation" | |
| 7/87 | Cantonsspital, Basel, Switzerland | |
| 2/88 | Emory University, Atlanta, Georgia | |
| 10/88 | University of Louisville, Louisville, KY | |
| 12/88 | University of Wisconsin, Madison, WI | |
| 12/89 | Gorden Conference on Angiotensin | |
| 3/89 | University of Florida, Gainesville, FL | |
| 11/89 | University of Kentucky, Lexington, KY | |
| 8/90 | Third International Vasopressin Conference, Montpellier, France, invited speaker | |
| 8/90 | CIBA-Geigy Ltd, Basel, Switzerland | |
| 8/90 | University of Heidelberg, Department of Pharmacology, Heidelberg, Germany | |
| 8/90 | Netherlands Brain Research Institute, Amsterdam | |
| 1/92 | Medical College of Wisconsin, Milwaukee, WI | |
| 6/92 | International Society for Hypertension, Madrid Spain | |
| 6/92 | CIBA-Geigy, Ltd. | |
| 7/92 | Neurohypophysis: A Window on Brain Function. Sponsored by New York Academy of Science and Dartmouth College | |
| 9/92 | Guest speaker for Hypertension Day - University of Tennessee, Memphis TN | |
| 10/93 | Tulane University, New Orleans, LA | |
| 3/94 | International Society for Hypertension, Melborne, Australia | |
| 3/94 | University of Auckland, Auckland, New Zealand | |
| 5/94 | Louisiana State University, New Orleans, LA | |
| 11/94 | University of Pittsburgh, Pittsburgh, PA | |
| 12/94 | University of Tennessee, Memphis, TN | |
| 1/95 | Michigan State University | |
| 8/97 | Castine, Maine - Hypertension Summer School | |
| 9/97 | San Destin, Florida - Hypertension Workshop | |
| 10/97 | University of Tennessee, Memphis | |
| 3/99 | University of Florida at Gainesville | |
| 7/99 | 3rd Hypertension Summer School, Boulder, CO | |
| 9/99 | International Conference on Fetal Origins of Adult Disease. Effects of prenatal therapy with ACE inhibitor or antisense (to the angiotensin II AT1 receptor) gene therapy. Sponsored by NIH-NICHHD | |
| 10/99 | National Institutes of Child Health and Human Development Workshop on Developmental Pharmacology. Effects of prenatal or neonatal therapy with ACE inhibitors or angiotensin receptor antisense in prevention of high blood pressure in adult spontaneously hypertensive rats. Possible relevance in humans. | |
| 4/00 | Department of Physiology, University of Minnesota, Minneapolis, MN | |
| 5/00 | Keynote Speaker, Ontario Chapter
of the Canadian Hypertension Society
|
|
| PARTICIPATION IN SCIENTIFIC MEETINGS | |
| 4/74 | FASEB, Atlantic City, New Jersey, slide presentation |
| 10/75 | APS, San Francisco, California, poster presentation |
| 8/76 | APS, Philadelphia, Pennsylvania, poster presentation |
| 10/76 | AHA, Council for High Blood Pressure, Cleveland, slide presentation |
| 10/77 | APS, Florida, poster presentation |
| 4/78 | Hypertension Workshop, Heidelberg, Germany, slide presentation |
| 7/78 | Third International Symposium for Vascular Neuroeffector Mechanisms, Louvain and Antwerpen, Belgium, slide and poster presentations |
| 12/78 | Scientific Sessions - Deutscheforschungsgemeinschaft, SBF-90, poster presentation |
| 2/79 | Hypertension Workshop, Mainz, Germany, slide presentation |
| 7/79 | Sixth congress, International Society for Hypertension, Goteborg, Sweden, slide presentation |
| 10/79 | APS, New Orleans, Louisiana, poster presentation |
| 4/80 | FASEB, Anaheim, California, slide presentation |
| 11/80 | American Heart, Miami, Florida, 2 slide presentations |
| 4/81 | FASEB, Atlanta Georgia, slide presentation |
| 9/81 | International Symposium on the Brattleboro Rat, Dartmouth, New Hampshire (1 slide and 2 poster presentations) |
| 9/81 | AHA, Council on High Blood Pressure, Cleveland, Ohio, slide presentation |
| 11/81 | AHA, Dallas, Texas, slide presentation |
| 1/82 | Southern Section AFCR, New Orleans, Louisiana, slide presentation |
| 4/82 | FASEB, New Orleans, Louisiana, slide presentation |
| 5/82 | AFCR, Washington, D.C., poster presentation |
| 7/82 | FASEB Workshop: Central Neural Mechanisms in Cardiovascular Regulation, Vermont, poster presentation |
| 9/82 | International Conference on the Neurohypophysis, Cambridge, Massachusetts, poster presentation |
| 10/82 | Southern Society of Pharmacologists, Seminar speaker |
| 1/83 | Southern Section, AFCR, New Orleans, Louisiana, slide presentation |
| 4/83 | FASEB, Chicago, Illinois, slide presentation |
| 11/83 | AHA, Anaheim, California, slide presentation |
| 1/84 | Southern Section, AFCR, New Orleans, Louisiana, slide presentation |
| 4/84 | FASEB, St. Louis, Missouri, slide and poster presentation |
| 6/84 | Seminar: Neuropeptides & Blood Pressure Control, Heidelberg, West Germany, slide |
| 6/84 | International Society for Hypertension 2 presentations, poster and slide |
| 1/85 | Southern Section, AFCR, New Orleans, Louisiana, 2 presentations, 1 poster, 1 slide |
| 5/85 | FASEB, Anaheim, slide presentation |
| 6/85 | Symposium Vascular Smooth Muscle in Hypertension New Port, RI, slide presentation |
| 9/85 | AHA Council for High Blood Pressure Research, slide presentation |
| 10/85 | Swiss Council for High Blood Pressure, Workshop on Vasopressin, seminar speaker, poster presentation |
| 11/85 | AHA, Washington, D.C., poster presentation |
| 4/86 | FASEB, St. Louis, Missouri, slide presentation |
| 9/86 | AHA Council for High Blood Pressure Research, poster presentation |
| 3/87 | FASEB, Washington, D.C., 2 slide presentations |
| 5/87 | InterAmerican Society for High Blood Pressure Research, Buenos Aires, Argentina |
| 6/87 | FASEB, Vermont Academy, Vermont, 1 slide presentation |
| 5/88 | FASEB, Las Vegas, Nevada, 1 poster |
| 8/88 | American Heart Assoc., Georgia Affiliate, Athens, GA, 1 slide presentation |
| 9/88 | San Francisco, CA - AHA Council for HBP Research Meeting, slide presentation |
| 11/88 | Neuroscience Meeting, Toronto, Canada, 1 slide presentation |
| 2/89 | Gordon Conference on Angiotensin, invited speaker |
| 3/89 | FASEB - 1 slide, Chaired a session |
| 5/89 | SHR Symposium, University of Iowa, 1 slide, 1 poster |
| 10/89 | AHA Council for High Blood Pressure Research, 1 slide, 1 poster |
| 4/90 | FASEB, Washington, D.C., 1 slide, 1 poster |
| 9/90 | AHA Council for High Blood Pressure Research, 1 slide |
| 11/90 | Society for Neuroscience, 1 slide |
| 4/91 | FASEB, 1 slide, 1 poster |
| 4/92 | FASEB, 1 poster, Chaired a session |
| 6/92 | International Society of Hypertension, 1 poster, Madrid, Spain |
| 3/93 | FASEB, 1 poster, Chaired session |
| 9/93 | Council for High Blood Pressure , Chaired session, 1 poster |
| 3/94 | International Society of Hypertension, 2 posters, Melbourne, Australia |
| 4/94 | FASEB, 1 slide, Chaired session, New Orleans, LA |
| 9/94 | Council for High Blood Pressure Research, 1 slide, Chaired session |
| 4/95 | FASEB, 1 slide, 1 poster, Chaired session, Atlanta, GA |
| 4/96 | FASEB, 1 slide, Chaired session, Washington, DC |
| 4/97 | FASEB, 1 slide, Chaired session, New Orleans, LA |
| 4/98 | FASEB, Chaired session, San Francisco, CA |
| 4/98 | Chair of "Vascular Growth, Hypertrophy, Remodeling at EB ‘98 Meeting, San Francisco, CA. |
| 5/98 | Council for High Blood Pressure, Executive Committee Meeting, New York International Society of Hypertension 2000 Program, New York City |
| 8/98 | NIH/NIDDK Site Visit, Denver, CO |
| 9/98 | Council for High Blood Pressure Research, 52nd Annual Fall Conference and Scientific Sessions, Philadelphia, PA International Society of Hypertension 2000 Program, Philadelphia, PA |
| 10/98 | AHA Peer Review Meeting, Dallas, TX |
| 11/98 | 71st Scientific Sessions, Dallas, TX International Society of Hypertension 2000 Program, Dallas, TX |
| 12/98 | APS Section Advisory & Nominating Committee, Bethesda, MD |
| 4/99 | FASEB, Chairman, Cardiovascular Section of American Physiological Society, Washington, DC – Chaired 2 symposia, 1 poster |
| 5/99 | Council for High Blood Pressure, Executive Committee Meeting, New York City International Society of Hypertension 2000 Program Committee - American Society of Hypertension Membership Committee, New York City |
| 5/99 | InterAmerican Society Meeting, Buenos Aires, Argentina – 1 slide presentation |
| 7/99 | 3rd Hypertension Summer School, Boulder, CO |
| 9/99 | AHA Council for High Blood Pressure Research |
| 10/99 | Hypertension Workshop, San Destin, FL –
Chaired session
|
| TEACHING EXPERIENCE | |
| Fall, 1982 | 4 cardiovascular laboratories, medical students |
| Spring, 1983 | 4 cardiovascular laboratories, dental students; 7 lectures-cardiovascular physiology dental students; 4 hour tutorial - Advanced Seminar Cardiovascular Physiology - graduate students |
| Fall, 1983 | 4 cardiovascular laboratories, medical students |
| Spring, 1984 | 7 lectures, cardiovascular physiology, dental students |
| Fall, 1984-85 | 12 lectures, 4 cardiovascular laboratories, medical students |
| Spring, 1985 | 6 lectures, 2 laboratories, dental students |
| Fall, 1985-86 | 7 lectures, 4 laboratories, medical students |
| Spring, 1986 | 6 lectures, 2 laboratories, dental students |
| Fall, 1986 | 4 labs, medical students |
| Spring, 1987 | 4 labs, dental students; 5 lectures, Neurosciences Program, graduate students |
| Fall, 1987 | Taught a graduate seminar, "Selected topics in Physiology" its theme was critical analysis of published scientific literature, research seminars and research grants. |
| Winter, 1988 | 7 hrs. medical school lectures, 4 laboratories |
| Spring, 1988 | 8 hrs. dental school lectures, 1 laboratory |
| Spring, 1988 | 6 hrs. lecture Neuroscience Training Program |
| Winter, 1989 | 6 hrs. lecture Neuroscience Training Program |
| Spring, 1989 | 8 hrs. lecture, 2 labs dental school |
| Winter, 1990 | 10 hrs. medical school lectures, 2 laboratories |
| Spring, 1990 | 6 hrs. dental school lectures; 4 hrs. Neuroscience program lectures |
| Fall, 1991 | 8 hrs. dental school lectures; 2 hrs. Neuroscience Program lectures |
| Winter, 1992 | 10 hrs. Medical School of Physiology; 5 hrs. Neuroscience Program lectures |
| Winter, 1993 | 2 hrs Neuroscience Program, 8 hrs Medical School Physiol.; 4 hrs Dental School; 2 hrs Neurophysiology course |
| Fall, 1994 | 2 hrs Molecular Physiology Course |
| Winter, 1994 | 2 hrs Neuroscience Program, 18 hrs Medical School |
| Fall, 1995 | 2 hrs Molecular Physiology Course |
| Winter, 1996 | 8 hrs Medical School; 6 hrs Dental School |
| Fall, 1996 | 2 hrs Cell and Molecular Physiology |
| Winter, 1997 | 4 hrs Lecture Medical Physiology; 6 hrs Laboratory Medical Physiology; 5 hrs Lecture Dental Physiology |
| Winter, 1998 | 8 hrs Lecture Dental/Optometry Physiology |
| Winter, 1998 | 6 hrs Moderator in Medical Physiology*3 hrs EKG Lab; 6 hrs Lecture Dental/Optometry Physiology |
| Winter, 1999 | 3 hrs EKG Lab; 4 hrs Small Group Discussion; 6 hrs Lecturer, Dental/Optometry/Physiology |
| Winter, 2000 | 3 hrs EKG Lab, Medical Physiology; 4 hrs Small Discussion Group; 4 hrs Graded Student Presentation; 6 hrs Lecturer, Dental/Optometry/Physiology |
COMPLETE PAPERS
1. Berecek, K.H. and Janson, S.L. Influence of postanesthetic suggestion on the prevention of postoperative pulmonary complications. Chest 61:240-246, 1972.
2. Berecek, K.H. Etiology of decubitus ulcer. Nrsg. Clin. N.A. 10:157-170, 1975.
3. Berecek, K.H. Treatment of decubitus ulcers. Nrsg. Clin. N.A. 10:171-210, 1975.
4. Berecek, K.H. and Bohr, D.F. Bases for increased vascular reactivity in experimental Hypertension. Proc. 2nd International Symposium on Vascular Neuroeffector Mechanisms. J. Bevan, et al, eds. S. Karger, Basel, 1976, pp 199-204.
5. Bohr, D.F. and Berecek, K.H. Relevance of vascular structural and smooth muscle sensitivity changes in hypertension. Aust. and New Zealand J Med. 6:(Suppl 2)26-34, 1976.
6. Terris, J.M., Berecek, K.H., Cohen, E.L., Stanley, J.C., Whitehouse, W.M., Jr. and Bohr, D.F. DOCA hypertension in the pig. Clin. Sci. 51:303-305, 1976.
7. Berecek, K.H. and Bohr, D.F. Structural and functional changes in vascular resistance and reactivity in the deoxycorticosterone acetate (DOCA) - hypertensive pig. Circ. Res., 40:(Suppl I)-146-152, 1977.
8. Berecek, K.H. and Bohr, D.F. Whole body reactivity during the development of deoxycorticosterone acetate hypertension in the pig. Circ. Res. 42:764-770, 1978.
9. Berecek, K.H., Rascher, W. and Gross, F. Vascular reactivity in the pathogenesis of spontaneous hypertension. Clin. Sci. 57:51-53s, 1979.
10. Dietz, R., Haebara, H., Schomig, A., Rascher, W., Berecek, K.H., Mann, J.F.E. and Luth, M.P. The role of the kidney in the pathogenesis of spontaneous hypertension in rats. Proc. 3rd International Symposium on the Spontaneously Hypertensive Rat. Jap. Heart J. 20:(Suppl I)52-54, 1979.
11. Ganten, D., Berecek, K., Kreye, V. and Rascher, W. Renin increases blood pressure. Lancet I:495, 1979.
12. Berecek, K.H. and Bohr, D.F. Evidence for a role for changes in vascular smooth sensitivity in the development deoxycorticosterone (DOCA) hypertension in the pig. Vascular Neuroeffector Mechanisms. J. Bevan, et al, eds. Raven Press: N.Y., 1980, pp. 368-370.
13. Berecek, K.H., Schwertschlag, U., and Gross, F. Alterations in renal vascular resistance and reactivity in spontaneous hypertension of rats. Amer. J. Physiol. 238:H287-293, 1980.
14. Berecek, K.H., Stocker, M. and Gross, F. Changes in renal vascular reactivity at various stages of deoxycorticosterone hypertension in rats. Circ. Res. 46:619-624, 1980.
15. Berecek, K.H., Murray, R.D. and Gross, F. Significance of sodium, sympathetic innervation and central adrenergic structures on renal vascular responsiveness in DOCA-treated rats. Circ. Res. 47:675-683, 1980.
16. Henrichs, K.J., Unger, T., Berecek, K.H. and Ganten, D. Is arterial media hypertrophy spontaneously hypertensive rats (SHR-sp) a consequence of or a cause for hypertension? Clin. Sci. 59:331s-333s, 1980.
17. Berecek, K.H., Murray, R.D., Gross, F. and Brody, M.J. Vasopressin and vascular reactivity in development of DOCA hypertension in rats with hereditary diabetes insipidus (DI). Hypertension 4:3-12, 1982.
18. Berecek, K.H. and Brody, M.J. Evidence for a neurotransmitter role for epinephrine derived from the adrenal medulla. Amer. J. Physiol., 242:593-601, 1982.
19. Berecek, K.H., Barron, K.W., Webb, R.L., and Brody, M.J. Vasopressin-Central nervous system interactions in the development of DOCA hypertension. Hypertension 4(Suppl II):II-131 - II-137, 1982.
20. Berecek, K.H. and Brody, M.J. Vasopressin and deoxycorticosterone hypertension in Brattleboro rats. In The Brattleboro Ra, H.W. Sokol and H. Valtin, eds. Annals N.Y. Acad. Sci., 394:319-329, 1982.
21. Berecek, K.H., Webb, R.L., Barron, K.W. and Brody, M.J. Vasopressin projections and central control of cardiovascular function in the Brattleboro rat. In The Brattleboro Rat, H.W. Sokol and H. Valtin, eds. Annals N.Y. Acad. Sci., 394:729-734, 1982.
22. Berecek, K.H., Barron, K.W., Webb, R.L. and Brody, M.J. Relationship between vasopressin and the anteroventral third ventricle region in deoxycorticosterone/salt hypertension (Brattleboro rat model) in the Brattleboro rat. In The Brattleboro Rat, H.W. Sokol and H. Valtin, eds. Annals N.Y. Acad. Sci., 394:392-397, 1982.
23. Berecek, K.H., Webb, R.L. and Brody, M.J. Evidence for a central role for vasopressin in cardiovascular regulation. Am. J. Physiol., 244:H852-H859, 1983.
24. Berecek, K.H., Okuno, T., Nagahama, S, and Oparil, S. Altered vascular reactivity and baroreflex sensitivity induced by chronic central administration of captopril in the spontaneously hypertensive rat (SHR). Hypertension 5:689-700, 1983.
25. Berecek, K.H., Olpe, H.R., Jones, R.S.G. and Hofbauer, K.G. Cardiovascular responses to microinjection of vasopressin into the locus coeruleus of conscious rats. Am. J. Physiol: Heart and Circulatory Physiol. 247:H675-H681, 1984.
26. Berecek, K.H., Nagahama, S. and Oparil, S. Effect of central administration of MK-422 (the diacid form of enalapril) on the development of hypertension in the spontaneously hypertensive rat. J. Hypertension 2(Suppl 3)63-66, 1984.
27. Berecek, K.H., Mah, S.C., Baum, R. and Hofbauer, K.G. Cardiovascular effects of intracerebroventricular injection vasopressin in unanesthetized normotensive and DOCA-salt hypertensive rats. J. Hypertension 2(Suppl 3):29-31, 1984.
28. Berecek, K.H., Work, J., Mitchum, T.N. and Ram, S. Effects of chronic peripheral sympathectomy on plasma levels of and the pressor response to vasopressin. J. Hypertension, 3:255-230, 1985.
29. Olpe, H.R., Berecek, K.H., Jones, R.S.G., Steinmann, M.W., Sonnenburg, C. and Hofbauer, K.G. Reduced activity of locus coeruleus neurons in SHR and DOCA-salt rats. Neuroscience Letters 61:25-29, 1985.
30. Olpe, H.R., Berecek, K.H., Jones, R.S.G., Steinmann, M.W., Sonnenburg, C. and Hofbauer, K.G. Reduced activity of locus coeruleus neurons in hypertensive rats. J of Hypertension 3(Suppl 4):S93-S95, 1985.
31 Berecek, K.H. and Mitchum, T.N. Role of vasopressin in the cardiovascular response to stimulation of the locus coeruleus. Endocrinology 118:1829-1834, 1986.
32. Berecek, K.H., Shier, D.N. Alterations in renal vascular reactivity induced by chronic central adminisration of captopril in the spontaneously hypertensive rat. Clinical and Experimental Hypertension A8(7):1081-1106, 1986.
33. Rademacher, R., Berecek, K.H. and Ploth, D.W. Effects of angiotensin inhibition and renal denervation in two-kidney one-clip hypertensive rats. Hypertension 8:1127-1134, 1986.
34. Berecek, K.H. Role of central vasopressin in cardiovascular regulation. J. Cardiovascular Pharmacology 8(Suppl 7):S76-S80, 1986.
35. Berecek, K.H., Olpe, H.R., Mah, S.C. and Hofbauer, K.G. Alterations in responsiveness of noradrenergic neurons of the locus coeruleus in DOCA-salt hypertensive rats. Brain Research 401:303-311, 1987.
36. Berecek, K.H., Kirk, K., Nagahama, S. and Oparil, S. Alterations in sympathetic function in spontaneously hypertensive rats after chronic administration of captopril. American Journal of Physiology: Heart and Circulatory Physiology, 252:H796-H806, 1987.
37. Berecek, K.H., Olpe, H.R., and Hofbauer, K.G. Enhanced responsiveness of locus coeruleus neurons in Deoxycorticosterone (DOCA)-salt hypertensive rats to microiontophoretically applied vasopressin. Hypertension, 9(Suppl III):III-110 - III-113, 1987.
38. Berecek, K.H., Coshatt, G., Narkates, A.J., Oparil, S., Wilson, K. and Robertson, J. Captopril and the response to stress in the spontaneously hypertensive rat. Hypertension 11(Suppl I):I-144 -I-147, 1988.
39. Wilson, K., Magargal, W. and Berecek, K.H. Long term captopril treatment: angiotensin II receptors and responses. Hypertension 11(Suppl I):I-148 - I-152, 1988.
40. Cheng, S.W.T., Swords, B.H., Kirk, K.A. and Berecek, K.H. Effect of lifetime captopril treatment on baroreceptor function in the spontaneously hypertensive rat. Hypertension 13:63-69, 1989.
41. Cheng, S.W.T., Wilson, K.M., Mulchahey, J.J., Stallworth, J.W. and Berecek, K.H. Vasopressin in neuronal cultures from neonatal rat brain. Hypertension, 13:902-909, 1989.
42. Cheng, S.W.T., Kirk, K.A., Robertson, J.D. and Berecek, K.H. Brain angiotensin II and baroreflex function in spontaneously hypertensive rats. Hypertension 14:274-281, 1989.
43. Swords, B.H., Carr D.J.J., Blalock, J.E. and Berecek, K.H. An antibody directed against a peptide encoded by RNA complementary to mRNA of vasopressin recognizes putative vasopressin receptors. Neuroendocrinology 51:487-492, 1990.
44. Berecek, K.H. and Swords, B.H. Central role for vasopressin in cardiovascular regulation and the pathogenesis of hypertension. Hypertension 16:213-224, 1990.
45. Lee, R.M., K.W., Berecek, K.H., Tsoporis, J., McKenzie, R. and Triggle, C.R. Prevention of hypertension and vascular changes in spontaneously hypertensive rats by captopril treatment. Hypertension 17:141-150, 1991.
46. Berecek, K.H., Robertson, J.D., and Hernandez Thorstad, M. Central administration of a specific angiotensin II receptor antagonist on baroreflex function in spontaneously hypertensive rats. J. Hypertension 9:365-371, 1991.
47. King S.J, Oparil S. and Berecek, K.H. Neuronal angiotensin converting enzyme (ACE) gene expression is increased by converting enzyme inhibitors (CEI). Mol. and Cell Neurosciences 2:13-20, 1991.
48. Swords, B.H., Green, M.M., Blalock, J.E., Berecek, K.H., and LeBoeuf, R.D.. Cloning and sequencing from lambda libraries using polymerase chain reaction and direct sequencing. Netherlands Journal of Medicine 39:295-305, 1991.
49. Swords, B.H., Wyss, J.M., and Berecek, KH. Central vasopressin receptors are upregulated by deoxycorticosterone acetate. Brain Research 559:10-16, 1991.
50. Berecek, K.H., Wyss, J.M., and Swords, B.H. Alterations in vasopressin mechanisms in captopril-treated spontaneously hypertensive rats. Clinical and Experimental Hypertension A13: (5):1019-1031, 1991.
51. Berecek, K.H., Swords, B.H., Lo, S., and Stallworth, J. Effect of angiotensin converting enzyme inhibitors on brain angiotensin II binding. Journal of Hypertension 10:545-552, 1992.
52. Wu, J.N. and Berecek, K.H. Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor captopril. Hypertension 22:139-146, 1993.
53. Oparil, S., Yang, R.H., Jin, H.G., Chen, S.J., Meng, Q.C., Berecek, K.H., Wyss, J.M. Role of anterior hypothalamic angiotensin II in the pathogenesis of salt-sensitive hypertension in the spontaneously hypertensive rat. Am. J Med. Sci. (Suppl 1)S26-S37, 1994.
54. Wu, J.N., Edwards, D., and Berecek, K.H.. The effect of captopril on renal angiotensin II receptors in spontaneously hypertensive rats. Hypertension 23(Part 2):819-822, 1994.
55. Wyss, J.M., Roysommati, S., King, K., Kadisha, I., Regan, C.P., and Berecek, K.H. Salt-induced hypertension in normotensive, spontaneously hypertensive rats. Hypertension 23(Part 2): 791-796, 1994.
56. Wu, J.N., Edwards D., Zhang, L., and Berecek, K.H. Effects of early treatment of spontaneously hypertensive rats with an angiotensin converting enzyme inhibitor on blood pressure, baroreflex function and cardiac hypertrophy. Hypertension Research: Clinical & Exper. 17:243-251, 1994.
57. Yang, R-H, Bunting, S., Wyss, J.M., Berecek, K.H., Zhang, L. and Jin, H. Pressor and bradycardiac effects of centrally administered relaxin in conscious rats. Am. J. Hypertension 8:375-381, 1995.
58. Zhang, L., Edwards, D.G., and Berecek, K.H. Effects of early captopril treatment and its removal on plasma angiotensin converting enzyme (ACE) activity and arginine vasopressin in spontaneously hypertensive rats (SHR) and normotensive rats (WKY). Clinical & Experimental Hypertension. 18:201-226, 1996.
59. Regan, C.P., Anderson, P.G., Bishop, S.P., and Berecek, K.H. Captopril prevents vascular and fibrotic changes but not cardiac hypertrophy in aortic-banded rats. AJP:Heart and Circulatory Physiology 271:H906-H913, 1996.
60. Regan, C.P., Anderson, P.G., Bishop, S.P., and Berecek, K.H. Pressure-independent effects of AT1 receptor antagonism on cardiovascular remodeling in aorta-banded rats. American Journal Physiology 272:H2131-H2138, 1997.
61. Regan C.P., Bishop, S.P., and Berecek, K.H. Early, short-term treatment with captopril permanently attenuates cardiovascular changes in spontaneously hypertensive rats. Clinical and Experimental Hypertension, 19:1161-1177, 1997.
62. Martens J.R., Reaves, P.Y., Lu, D., Katovich, M.J., Berecek, K.H., Bishop, S.P., Raizada M.K., and Gelband, C.H. Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy. Proc. Nat’l. Acad. of Sci., USA, 95(5):2664-2669, 1998.
63. Keaton, A.K., White, R., and Berecek, K.H. The effects of long-term captopril treatment and its withdrawal on acetylcholine-induced relaxation in the spontaneously hypertensive rat. Clin. and Exper. Hypertension 20(8) 847-866, 1998.
64. Fang, Z, Sripairojthikoon, W., Calhoun, DA, Zhu, S., Berecek, KH, Wyss, JM. Lifetime captopril exacerbates NaCl-sensitive hypertension in spontaneously hypertensive rats and Wistar Kyoto rats. J. Hypertension.17:983-991, 1999.
65. Fang, Z. Berecek, K.H. and Wyss, J.M. Dietary NaCl-sensitive hypertension in one-year-old spontaneously hypertensive rats and lifetime captopril-treated Wistar Kyoto rats. Hypertension. (In press)
66. Roysommuti, S., Mozaffari, M.S., Berecek, K.H., and Wyss, J.M. Lifetime treatment with captopril improves renal function in spontaneously hypertensive rats. Clin. and Exper. Hypertension. 21:1315-1325, 1999.
67. Reaves, P.Y, Gelband, C.H, Wang, H., Lu, D., Berecek, K.H., Yang, H., Katovich, M.J., Raizada, M.K. Permanent cardiovascular protection by AT1R-AS gene therapy in hypertensive rat offspring. Circulation Res 85:44-50, 1999.
68. Raizada, M.K., Katovich, M.J., Wang, H., Berecek, K.H., and Gelband, C.H. Is antisense gene therapy a step in the right direction in the control of hypertension? AJP: Heart and Circulatory Physiology. Amer. J. Physiol. 277:H423-H32, 1999.
69. Carley DW, Berecek KH, Videnovic A and Radulovacki M. Sleep-disordered respiration in phenotypically normotensive, genetically hypertensive rats. Am J Respir Crit Care Med 162:1474-1479, 2000.
70. Gardon M, Raizada MK, Katovich MJ, Berecek KH and Gelband CH. Gene therapy for hypertension and restenosis. JRAAS 1/3:211-216, 2000.
71. Barry, W.T., Berecek, K.H., Edwards, D.G., and Speth, R.C. Captopril induced alterations in brain angiotensin II receptors in spontaneously hypertensive rat pups. (Submitted to Hypertension)
72. Berecek, K.H., Reaves, P.Y, Katovich, M.J, Gelband, C.H., and Raizada, M.K. Vascular morphology in offspring of spontaneously hypertensive rats (SHR) treated with angiotensin type 1 receptor antisense gene therapy. (Submitted to Hypertension)
CONTRIBUTIONS IN A BOOK
1. Berecek, K.H. and Brody, M.J. Effects of stimulation of central pressor and depressor areas in SHR. Hypertensive Mechanisms: The Spontaneously Hypertensive Rat as a Model to Study Human Hypertension. Proc. 4th International Symposium on Rats with Spontaneous Hypertension and Related Studies, Rascher W., Clough D. and Ganten, D. eds. F.K. Schattauer Verlag: Stuttgart pp 394-397, 1982.
2. Brody, M.J., Barron, K.W., Berecek, K.H., Faber, J.E. and Lappe, R.W. Neurogenic mechanisms of experimental hypertension. Hypertension J. Genest, O. Kuchel, P. Hamet and M. Cantin eds. McGraw-Hill:N.Y.; 1983, pp 117-140.
3. Berecek, K.H. and Hofbauer, K.G. Neuropeptides as modulators of blood pressure. In Progress in Hypertension (Vol. I) Neurotransmitters as Modulators of Blood Pressure. H. Saito, H. Parvez, S. Parvez and T. Nagatsu, eds. VNU Int. Science Press, Utrecht, Holland, 1988, pp 231-260.
4. Swords, B.H., Wyss, J.M., and Berecek, K.H. Vasopressin and vasopressin receptors are enhanced in the central nervous system in deoxycorticosterone NaCl Hypertension. In: Vasopressin, Jard S, Jamison R, eds. Paris: Colloque Inserm/John Libbey Eurotext Ltd.; 1991, pp 3-11.
5. Berecek, K.H., King, S.J., and Wu, J-N. Angiotensin Converting Enzyme and Converting Enzyme Inhibitors, in Cellular and Molecular Biology of the Renin-Angiotensin System, CRC Press, Inc., Boca Raton, Florida, 1993, pp 183-220.
6. Berecek K.H. Role of vasopressin in central cardiovascular regulation in Central Neural Mechanisms in Cardiovascular Regulation, Vol 2, G. Kunos and J. Ciriello, eds Birkhauser: Boston, 1992 pp. 1-34.
7. Berecek, K.H. and Wyss, J.M. Catecholamine receptors and actions. In Hypertension Primer, J. Izzo and H. Black eds, American Heart Association 1993.
8. Oparil, S., Chen, Y-F., Berecek, K.H., Calhoun, D.A., and Wyss, J.M. The role of the central nervous system in hypertension. In Hypertension: Pathophysiology, Diagnosis and Management. J.H. Laragh, B.M. Brenner, eds, Raven Press: NY, 1995, pp. 713-740.
9. Berecek, K.H. and Zhang, L. Biochemistry and cell biology of angiotensin-converting enzyme and converting enzyme inhibitors. In Tissue Renin-Angiotensin Systems. A.K. Mukhopadhyay and M.K. Raizada, eds. Plenum Press, NY 1995, pp. 141-168.
10. Berecek, K.H. and Klett, C.P. Contributions of Renin-Angiotensin Systems to the Development of Hypertension in Development of the Hypertensive Phenotype: Basic and Clinical Studies, Handbook of Hypertension series, Volume 19, McCarty, R, Blizard, DA and Chevalier, RL, eds. Elsevier Publishing, Amsterdam, pp 327-358, 1999.
11. Berecek, KH and Carey R. Adrenergic and dopaminergic receptors and actions. Hypertension Primer, Izzo, JL, Jr. and Black, HR, eds. American Heart Association, pp 3-6, 1999.
12. Meng, Q-C and Berecek, KH. Quantification of Angiotensin-Converting Enzyme (ACE) Activity. Methods in Molecular Medicine. D. Wang, ed. Humana Press Inc., New Jersey, 2000.
13. Meng, Q-C and Berecek, KH. Quantification of Angiotensin Peptides. Methods in Molecular Medicine. D.H. Wang ed. Humana Press Inc., New Jersey, 2000.
ABSTRACTS
1. Berecek, K.H. and Bohr, D.F. Vascular reactivity to norepinephrine in renal hypertensive rats. Fed Proc 34:382, 1975.
2. Berecek, K.H. and Bohr, D.F. Vascular reactivity in renal and DOCA hypertensive rats. The Physiologist 18:139, 1975.
3. Bohr, D.F. and Berecek, K.H. Bases for increased vascular reactivity in experimental hypertension. Blood Vessels 12:332-333, 1975.
4. Berecek, K.H. and Bohr, D.F. Vascular reactivity in the DOCA hypertensive pig. The Physiologist 19:124, 1976.
5. Terris, J.M., Cohen, E.L., Berecek, K.H., Stanley, J.C., White, D.C. and Bohr, D.F. DOCA hypertension in the pig. Fed. Proc. 35:770, 1976.
6. Berecek, K.H. and Bohr, D.F. Systemic vascular reactivity in the DOCA hypertensive pig. The Physiologist 20:8, 1977.
7. Berecek, K.H., Bohr, D.F. Functional changes in vascular smooth muscle in the DOCA hyper- tensive pig. Abstracts, 5th Scientific Meeting of the International Society of Hypertension, 1978.
8. Berecek, K.H., Rascher, W., and Gross, R. Changes in vascular reactivity in perfused hindlimb and kidney of young stroke-prone spontaneously hypertensive rats (spSHR). Blood Vessels 16:208-209, 1979.
9. Berecek, K.H., Murray, R.D., and Gross, R. Increased vascular reactivity as a primary mechanism in spontaneous and deoxycorticosterone hypertension in rats. The Physiologist 22:9, 1979.
10. Berecek, K.H., Shaffer, R.A., and Brody, M.J. Mechanisms of the hind limb vasodilator response to activation of the anteroventral third ventricle (AV3V) region. Fed Proc 39:3643, 1980.
11. Berecek, K.H., Murray, R.D., Brody, M.J., and Gross, R. Vasopressin (VP) and vascular reactivity in the development of deoxycorticosterone hypertension in rats with hereditary diabetes insipidus (DI). Circulation, 62:III-24, 1980.
12. Berecek, K.H., Shaffer, R.A., and Brody, M.J. Circulating epinephrine (Epi) is the source for the sympathetic transmitter mediating active beta-adrenergic vasodilation. Circulation, 62:III-221, 1980.
13. Berecek, K.H., Barron, K.W., Webb, R.L., and Brody, M.J. Vasopressin (VP) and the anteroventral third ventricle (AV3V) region in DOCA hypertension. Fed Proc 40:390, 1981.
14. Berecek, K.H. and Brody, M.J. Vasopressin projections and central control of cardiovascular function. International Symposium on the Brattleboro Rat, 1982.
15. Berecek, K.H. and Brody, M.J. Vasopressin and deoxycorticosterone hypertension in rats with hereditary diabetes insipidus. International Symposium on the Brattleboro Rat, 1982.
16. Berecek, K.H., Allen, D., and Brody, M.J. Cardiovascular effects of paraventricular nucleus stimulation in normal and DOCA hypertensive rats (DHR). Fed Proc 41:5772, 1982.
17. Berecek, K.H., Webb, R.L., Allen, D., and Brody, M.J. Central vasopressin (VP) projections and cardiovascular (CV) function. American Heart Association, 1982.
18. Berecek, K.H., Nagahama, S., and Oparil, S. Altered vascular reactivity (VR) and baroreflex sensitivity induced by central administration of captopril (CP) in the spontaneously hypertensive rat (SHR). Clinical Research 30:848A, 1982.
19. Berecek, K.H., Winternitz, S.R., and Oparil S. Enhanced sympathetic vasoconstrictor tone during high sodium (Na+) intake in the spontaneously hypertensive rat (SHR). Fed Proc, 42:1261, 1983.
20. Berecek, K.H., Winternitz, S.R., Wyss, J.M., and Oparil S. Exaggerated responsiveness to central sympathetic and alpha adrenergic stimulation in spontaneously hypertensive rats receiving high sodium intake. Clinical Research 31:487A, 1983.
21. Berecek, K.H., Nagahama S., Mitchum T.N., and Oparil S. Attenuation of hypertension in the spontaneously hypertensive rat (SHR) by chronic central administration of MK-422. Clinical Research 31:843A, 1983.
22. Berecek, K.H., Nagahama, S., Mitchum, T.N., and Oparil, S. Attenuated responsiveness to sympathetic stimulation in spontaneously hypertensive rats (SHR) after chronic central administration of captopril. Circulation 68: Supp III, 385, 1983.
23. Berecek, K.H., Olpe H., Jones, R.E., and Hofbauer, K.G. Cardiovascular (CV) responses to microinjection of vasopressin (AVP) into the locus coeruleus (LC) of the conscious rat. Fed Proc 43:1068, 1984.
24. Work, J., Berecek, K.H., Mitchum, T., and Ram, S. Effect of chronic sympathectomy (SX) on plasma levels of vasopressin (PAVP) and pressor sensitivity to vasopressin (VP) in rats. Fed Proc 43:896, 1984.
25. Berecek, K.H., Olpe, H., Jones, R.S., and Hofbauer, K.G. Cardiovascular (CV) effects of injection of vasopressin (AVP) into the locus coeruleus (LC) of the conscious rat. Proceedings of the Symposium on Neuropeptides and Blood Pressure Control Heidelberg, West Germany pg. 41, 1984.
26. Berecek, K.H., Mah, S.C., Baum, P., and Hofbauer, K.G. Cardiovascular (CV) effects of intracerebro-ventricular (ICV) injection of vasopressin (AVP) in unanesthetized normotensive and hypertensive rats. Proceeding 10th Meeting of the International Society of Hypertension, June, 1984.
27. Berecek, K.H., Okuno, T., Nagahama, S., and Oparil, S. Effect of central administration of converting enzyme inhibitors (CEI) on the development of hypertension in the spontaneously hypertensive rat (SHR). Proceedings of the 10th Meeting of the International Society of Hypertension, June, 1984.
28. Berecek, K.H. and Mitchum, T.N. Evidence for participation of vasopressin in central neural regulation of the cardiovascular system. Clinical Research 32:826A, 1984.
29. Shier, D.N., Robertson, J., Benn, K., and Berecek, K.H. Evidence that sodium (Na+) retention closely precedes the development of hypertension in the deoxycorticosterone (DOCA)/Salt treated rat. Clinical Research 32:845A, 1984.
30. Berecek, K.H. and Robertson, J. The effects of electrical stimulation and lesion of the locus coeruleus (LC) in DOCA/salt hypertensive rats (DHR). Fed. Proc. 44:6686, 1985.
31. Berecek, K.H. Locus coeruleus and central effects of vasopressin in DOCA/salt hypertensive rats. Hypertension 7:849, 1985.
32. Shier, D.N. and Berecek, K.H. Subpressor vasopressin (VP) enhancement of norepinephrine (NE) dose response is greater in DOCA hypertension. Circulation 72:III-420, 1985.
33. Berecek, K.H., Olpe, H-R., and Hofbauer, K.G. Enhanced responsiveness of noradrenergic (NA) neurons of the locus coeruleus (LC) of DOCA-salt hypertensive rats to microiontophoretic application of vasopressin (AVP). Fed. Proc. 45:392, 1986.
34. Shier, D. N., Rousseau, R., and Berecek, K.H. Subpressor vasopressin infusion potentiates the renovascular response to norepinephrine in DOCA-salt hypertensive rats. Fed. Proc. 45:895, 1986.
35. Berecek, K.H., Olpe, H.R., and Hofbauer, K.G. Alterations in responsiveness of noradrenergic (NA) neurons of the locus coeruleus (LC) in DOCA/salt hypertensive rats (DHR). Hypertension, 8:829, 1986.
36. Wilson, K.M., Robertson, J., and Berecek, K.H. Captopril and central angiotensin II (ANG II) receptors in the spontaneously hypertensive rat (SHR). Fed. Proc. 40:968, 1987.
37. Berecek, K.H., Wilson, K.M., and Magargal, W.W. Effect of chronic captopril (CP) treatment on peripheral vascular reactivity and angiotensin II (AII) receptor binding in SHR. Fed. Proc. 40:802, 1987.
38. Coshatt, G., Narkates, A., Robertson, J., Oparil, S., and Berecek, K.H. Brain Renin-Angiotensin (AII) and the response to stress in the spontaneously hypertensive rat (SHR). Fed. Proc. 40:1239, 1987.
39. Berecek, K.H., Coshatt, G., Narkates, A.J., Oparil, S., and Robertson, J. Brain renin-angiotensin system and the response to stress in the spontaneously hypertensive rat. Hypertension 9:527, 1987.
40. Berecek, K.H., Wilson, K.M., and Magargal, W.W. Effect of lifetime captopril treatment on drinking, peripheral vascular reactivity and angiotensin II (AII) receptor binding in SHR. Hypertension 9:527, 1987.
41. Cheng, S., Swords, B., Kirk, K., and Berecek, K. Effects of lifetime captopril treatment on baroreceptor function in the spontaneously hypertensive rat (SHR). The FASEB Journal 2: A717, 1988.
42. Wilson, K., Cheng, S., and Berecek, K. Vasopressin (VP) in neuronal cultures from neonatal rat brain. The FASEB Journal 2:A1153, 1988.
43. Cheng, S.W.T., Wilson, K.M., and Berecek, K.H. Measurements of vasopressin (VP) in primary neuronal cultures from rat brain. Hypertension 12:356, 1988.
44. Berecek, K.H. and Cheng, S.W.T. Enhanced baroreflex sensitivity in captopril (CAP) treated SHR is due to an inhibition of brain angiotensin II (AII) mechanisms. Hypertension 12:347, 1988.
45. Berecek, K.H. and Cheng, S.W.T. Enhanced baroreflex sensitivity in captopril (CAP) treated SHR is due to an inhibition of brain angiotensin II (AII) mechanisms. Neuroscience Abst. 14:915, 1988.
46. Swords, B.H. and Berecek, K.H. Enhanced 3H-vasopressin (3H-AVP) binding in deoxycorticosterone acetate (DOCA)-treated primary neuronal cultures. The FASEB Journal 3:A-725, 1989.
47. Berecek, K.H., Wyss, J.M., Swords, B.H., and Stallworth, J. Vasopressin (AVP) mechanisms in captopril (CAP) treated spontaneously hypertensive rats (SHR). The FASEB Journal 3:A-585, 1989.
48. Chen, F.P., Cheng, S.W.T., Robertson, J., and Berecek, K.H.. L-glutamate (GLU) stimulation of the locus coeruleus (LC) increases arterial pressure (AP) in conscious rats. The FASEB Journal 4:A1193, 1990.
49. Berecek, K.H., Swords, B.H., and Stallworth, J. Effects of angiotensin converting enzyme inhibitors (CEI) on brain angiotensin II (AII) binding. The FASEB Journal 4:A868, 1990.
50. Swords, B.H. and Berecek, K.H. Effects of deoxycorticosterone acetate (DOCA) on neuronal vasopressin (AVP) binding. The FASEB Journal 4:A1067, 1990.
51. King, S.J., Robertson, J., Stallworth, J., and Berecek, K.H. The effect of angiotensin-converting enzyme (ACE) inhibitors on ACE mRNA in neuronal cells. The FASEB Journal 4:A992, 1990.
52. Lee, R.M., Berecek, K.H., McKenzie, R., Tsoporis, J., and Triggle, C.R. Prevention of hypertension and cardiovascular changes by chronic captopril treatment in the spontaneously hypertensive rat. Journal of Hypertension 8(Suppl 3):S5, 1990.
53. Swords, B.H., LeBoeuf, R.D., Berecek, K.H., and Blalock, J.E. Application of the molecular recognition theory to the cloning and sequencing of the arginine vasopressin (AVP) receptor. FASEB Journal 4:A2142, 1990.
54. Berecek, K.H. and Swords, B.H. Effects of angiotensin converting enzyme inhibitors (CEI) on brain angiotensin II (AII) binding. Hypertension 16(3):320, 1990.
55. Berecek, K.H., Chen, Y.F., and Oparil S. Atrial natriuretic peptide (ANP) in neuronal cells from normotensive (WKY), spontaneously hypertensive (SHR) and captopril (CAP) treated rats. FASEB Journal 5:A1068, 1991.
56. King, S.J., Berecek, K.H., and Oparil S. Angiotensin converting enzyme (ACE) inhibitors enhance ACE gene expression. Ameican Journal of Hypertension, 4:81A, 1991.
57. Wu J.N., Zhang, L., Moellering, D., Francis, S., Tjepkes, D., King, S., and Berecek, K.H. Early Treatment of spontaneously hypertensive rats (SHR) with the angiotensin (AII) converting enzyme inhibitor captopril (CAP) prevents the subsequent development of hypertension and decreases central AII responses. FASEB Journal 6(4):A945, 1992.
58. Wu J.N., Zhang, L., King, S., Edwards, D., and Berecek, K.H. Early treatment with captopril (CAP) permanently alters hypertension in spontaneously hypertensive rats (SHR). Hypertension, 20: 401,1992
59. King, S.J., Berecek, K.H., Oparil, S., Rydzewski, B., and Raizada, M. Angiotensin-converting enzyme (ACE) gene expression is decreased after exposure to angiotensin II (Ang I) in vitro. FASEB Journal 6(4):A946, 1992.
60. Berecek, K.H., King, S.J., Wu, J.N., Oparil, S., Rydzewski, B., and Raizada, M. Effects of angiotensin II (AII) in the presence and absence of subtype-specific AII blockers on angiotensin converting enzyme (ACE) gene expression in central nervous system tissue. FASEB Journal 6(4):A1578, 1992.
61. Lee R.M.K.W., Li, C.Y., and Berecek, K.H.. Permanent cardiovascular changes with captopril treatment. To be published in proceedings of The Canadian Federation of Biological Sciences Symposia.
62. Berecek, K.H., Wu, J.N., and Zhang, L. Early treatment of the spontaneously hypertensive rat (SHR) with captopril (CAP) prevents the subsequent development of hypertension. Published in Proceedings of The 14th Scientific Meeting of The International Society of Hypertension, 1992.
63. Wu, J.N., Edwards, D., Zhang, L.H., and Berecek, K. H., Long term effect of an angiotensin converting enzyme inhibitor on baroreflex function in spontaneously hypertensive rats. FASEB Journal.F:A546. 1993.
64. Zhang, L., Wu, J.N., and Berecek, K.H. Effect of captopril treatment on plasma AVP of spontaneously hypertensive rats. FASEB Joournal F: A547, 1993.
65. Berecek, K.H., Wu, J.N., and Edwards, D. Alterations in renal angiotensin II receptors binding in captopril (CAP) treated spontaneously hypertensive rats (SHR). Hypertension 22:409, 1993.
66. Wu, J.N., Edwards, D., and Berecek, K.H. Early administration of captopril (CAP) to spontaneously hypertensive rats (SHR) and its antihypertensive effect. Hypertension 22:443, 1993.
67. Wyss, J.M., King, K., Roysommuti, S., Kadesha, Il, Ping, N., and Berecek, K.H. Salt sensitivity in spontaneously hypertensive rats made permanently normotensive by lifetime treatment with captopril. Hypertension 22:463, 1993.
68. Regan, C.P., Bishop, S.P., and Berecek, K.H. Captopril (CAP) prevents coronary vascular lesion and perivascular fibrosis but not hypertrophy in aortic banded (AB) rats. FASEB Journal 8:A794, 1994.
69. Berecek, K.H, Edwards, D., and Wu, J.N. Alterations in brain angiotensin II (AII) binding in brains and primary neuronal cultures (PNC) from captopril (CAP) treated spontaneously hypertensive rats (SHR). FASEB Journal 8A27, 1994.
70. Berecek, K.H. and Wu, J.N. Alterations in hypothalamic-brain stem angiotensin II (AII) receptor binding in captopril (CAP) treated spontaneously hypertensive rats (SHR). Abstracts Society for Neuroscience 19:1271, 1993.
71. Francis, S.C., Zhang, L., Wyss, J.M., and Berecek, K.H. Captopril treatment causes alterations in arginine vasopressin (AVP) in the plasma and brains of spontaneously hypertensive rats (SHR). FASEB Journal 8:A44, 1994.
72. Regan, C.P., Bishop, S.P., and Berecek, K.H. Captopril (CAP) prevents coronary vascular lesions and perivascular fibrosis but not hypertrophy in aortic banded rats (abstract). FASEB 8:A794, 1994.
73. Regan, C.P., Berecek, K.H., and Bishop, S.P. Early, short term treatment with captopril permanently prevents cardiovascular changes in spontaneously hypertensive rats. Journal of Hypertension 12:5213, 1994.
74. Berecek, K.H., Regan, C.P., Edwards, KD. And Wyss, J.M. High salt diet reverses antihypertensive effect of lifetime captopril treatment in spontaneously hypertensive rats. Hypertension. 24(3):397, 1994.